Membrane Protein Research Group
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About the Membrane Protein Research Group
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University of Alberta
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Membrane Protein Research Group
Our Goals
Our Goal

Our goal is to undertake a multidisciplinary approach to studies of the expression, assembly, structure and function of prokaryotic and eukaryotic membrane proteins and as well, to provide an outstanding training environment for undergraduates, graduate students and postdoctoral fellows in the area of membrane biology and related areas.

Scientists from major international and national research centers visit our group to present lectures. Weekly research seminars are held where members of the Group present major developments in their laboratories and share new ideas and techniques.

 

Research opportunities

Graduate student positions are available in the laboratories of Drs. Joe Casey, Emannuelle Cordat, Larry FliegelJoanne Lemieux , Todd Alexander, Elaine Leslie.  Link to the investigators name above or click here.

 
 
News
Upcoming Events
News
December 8, 2009

Dr. Jonathan Lytton, Professor and Chair,
Dept. of Biochemistry and Molecular Biology, University of Calgary
visited the MPRG and Department of Physiology, December 8, 2009.
Dr. Lytton presented at the Colliquia in Physiology Seminar Series. His seminar was entitled:
"K-Dependent Na/Ca-Exchangers: Novel Roles for Key Calcium Transporters".

December 1, 2 2009

Dr. Sergio Grinstein visited the Departments of Biochemistry, Physiology and the MPRG group on December 1 & 2nd. Dr. Grinstein is a senior scientist in the The Hospital for Sick Children Research Institute, holder of the Pitblado Chair in Cell Biology at The Hospital for Sick Children (SickKids), and a professor of Biochemistry at the University of Toronto.
He presented a seminar on Tues. December 1, 2009, entitled: "Signaling phagocytosis: receptors, phospholipids and charges".

October 22, 2009

Dr. Susan P.C. Cole visited the Departments of Physiology & Biochemistry, hosted by Dr. Elaine Leslie on October, 22.09. Dr. Cole is Professor Pathology & Molecular Medicine and Pharmacology & Toxicology, Queen's University.
She presented a seminar at the MPRG Seminar Series entitled: "Multiple Roles of Cytoplasmic Loops for Expression and Function of the ATP-binding Cassette Transporter MRP1".


Joel Weiner's lab
is relocating to 4-043 KGR -Katz Group Rexall Centre for Pharmacy and Health Research. We wish them the best in their move!

Congratulations to our 2009 Summer Student Seminar Award Winners!
1st - Vimarsha Swami (Fliegel lab)
2nd
- Andrew Rasmussen (Alexander lab)
3rd - Sandy Goodier (Duszyk lab).
Each presenter can be proud for a job well done. To all the MPRG summer students, thank you for your contributions to the group!

MPRG Annual BBQ was held on Friday, August 28.09.
A special thank you to Pam Bonar and her crew for putting together a great (and tasty) BBQ. Thanks to the many people who pitched in to help with shopping, set up and clean-up.

June 25, 2009
Best wishes to Barbara Roggenback from Dr. Elaine Leslie's lab. Barbara recently received an AHFMR studentship.

June 11, 2009
Dr. Masa Numata, Assistant Professor of Biochemistry and Molecular Biology, University of British Columbia was welcomed as a visiting speaker sponsored by the MPRG and the AHFMR. Dr. Numata gave a lecture entilted: "Na+/H+ exchangers in the brain: Potential roles in neuronal differentiation" which was very informative.

June 4 & 5, 2009
ALBERTA/GERMANY JOINT MEMBRANE TRANSPORT SYMPOSIUM
Thank you to all those who attended and volunteered. The Symposium by all regards, was a huge success!
Symposium Highlights (pictures)
Building Ties (pictures)

March 15, 2009
Congratulations to Elaine Leslie and her husband Rob on the arrival of their son, Graeme Robert.

March 6, 2009
Congratulations to Todd and Klaudia Alexander on the birth of their daughter, Marion Kenna!  All are doing well.

February 25, 2009
Congratulations to Dr. Joanne Lemieux, who was awarded a Canada Research Chair Salary award. Joanne was named a second tier Canada Research Chair in Membrane Protein Structure and Function. Her research centres around studying membrane proteins involved in disease, using X-ray crystallography and other biophysical techniques, to reveal functional and mechanistic details of membrane proteins that could one day aid in the development of new drugs and vaccines targeted towards membrane proteins. ...more

January 26, 2009
Elaine Leslie's Lab
has moved!  The Leslie lab has joined other MPRG researchers (Duszyk, Chen, Touret, Cordat, J. Young, Cheeseman and Casey) on the 7th floor of the Medical Sciences Building, Room 710.

   
Guest Speaker
Upcoming Events

MPRG Group Meetings are held each Thursday in HMRC 207 at 8:30 am.
February 11, 2010, Dr. Alex Gong, Research Associate (Dr. Marek Duszyk's lab) will present: "Structure, Function and Application of Antimicrobial Peptide
Carnocyclin A ."
Schedule for 2009-2010 is posted (here) .

Membrane Protein Journal Club is held Wednesdays in Room 4-70 MSB.
Wednesday, February 10, 2010, Delaine Ceholski will present: "Structure of the outer membrane complex of a type IV secretion system" (Bioch 640.pdf here)
Schedule for 2009-2010 is posted (here).

The MPRG are acting as hosts and organizing committee for an International Membrane Protein meeting.
REGISTRATION IS NOW OPEN!  Please link (here) to the registration page.
Register early and take advantage of the early bird special rates.

CSBMCB Homepage


Structure of rhomboid intramembrane protease solved by MPRG researcher,
Dr. Joanne Lemieux (from Proc Natl Acad Sci U S A. 2007 Jan 16;104(3):750-4).

 

Structure of transmembrane domain VII of the mammalian NHE1 isoform of the Na+/H+ exchanger from  Dr. Larry Fliegel's laboratory (J. Biol. Chem., 2006, 281:29817).